Use the table below to browse our clinical evidence or sort by keyword. To access the data click the ‘View’ column.
|wdt_ID||Category||Author||Key Findings||Purpose||Setting||What was being adhered?||View Data|
|1||Adherence||Mikhail et al.¹||Mastisol was found to be significantly better than TOB in increasing adhesiveness.||Compared Mastisol and tincture of benzoin (TOB) for their abilities to increase the adhesive power of wound closure strips.||Artificial clinical setting/volunteers||Wound closure strips||View|
|2||Adherence||Moy et al.²||Mastisol significantly increased the adhesiveness of all wound closure tapes tested.||Evaluated adhesive properties of 7 different wound closure tapes with and without Mastisol.||Artificial clinical setting/volunteers||Wound closure tapes||View|
|3||Adherence | Patient Safety||Lesesne³||After 5 days, 60 (40%) patients in the TOB-treated group vs 10 (7%) in the Mastisol-treated group showed signs of loss of adhesiveness. Temporary contact dermatitis developed in 38% of the TOB-treated patients vs 0.7% of the Mastisol-treated patients. Four patients in the TOB-treated group developed superficial skin infections vs none in the Mastisol group.||Compared Mastisol and TOB for adhesive properties and potential complications in a study of 300 patients with woundclosure strips.||Surgical suite||Wound closure strips||View|
|4||Adherence||Katz et al.⁴||Failure to coat the entire skin surface with Mastisol was detrimental to strip adherence.||Investigated the optimal pattern of surgical strips needed to maximize adhesiveness.||Artificial clinical setting/volunteers||Wound closure strips||View|
|5||Adherence | Patient Safety||Yavuzer et al.⁵||Mastisol significantly increased the adherence of adhesive strips. Mastisol significantly improved the burst strength of wounds closed with adhesive strips alone.||Compared burst strength of skin closure with sutures alone vs sutures with adhesive strips, with and without Mastisol.||Artificial laboratory setting/cadavers||Wound closure strips||View|
|6||Adherence||Patel et al.⁶||Pretreatment of the skin with Mastisol significantly increased the pullout force needed to dislodge the catheter for all tapes studied, either alone or with TOB pretreatment.||Investigated “pullout force” needed to dislodge IV catheter secured with various tapes, both alone and with the addition of TOB or Mastisol.||Artificial clinical setting/volunteers||Tapes attached to IV catheter||View|
|7||Patient Safety||James et al.⁷||16/~4500 cadets (0.3%) treated with TOB developed contact dermatitis severe enough to render them unfit for duty. 0/2200 (0%) cadets treated with Mastisol over 2 years developed contact dermatitis.||Evaluated West Point military cadets during basic training for allergic contact dermatitis following treatment for friction blisters with TOB or Mastisol.||Military clinical setting||N/A||View|
|8||Patient Safety||Klein et al.⁸||Clinician unable to work for 10 days while dermatitis was treated.||Described severe contact allergic dermatitis in anesthesiologist exposed to tincture of benzoin.||Operating room||Small bandage with TOB||View|
|9||Patient Safety||Ryder and Duley⁹||No significant difference in the reduction of normal skin flora was observed on skin prepped with CHG/IPA vs skin prepped with CHG/IPA followed by Mastisol or Detachol. Use of Mastisol or Detachol did not affect the antiseptic effectiveness CHG/IPA.||Evaluated compatibility of 2% clorhexidine gluconate/70% isopropyl alcohol (CHG/IPA) with Mastisol and Detachol to determine whether either product affected the antiseptic effectiveness of CHG/IPA.||Laboratory setting/ volunteers||N/A||View|
|10||Adherence | Patient Safety||Deneau and Craig¹⁰
Cookeville Regional Medical Center
|With Mastisol use, fewer dressings were compromised prior to 7 days. | Nursing staff noted less damage to patients’ skin while productivity was maintained.||Evaluated effectiveness of Mastisol for enhancing CVC dressing securement and preventing detachment.||ICU||CVC dressings||View|
|Category||Author||Key Findings||Purpose||Setting||What was being adhered?||View Data|
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- Mikhail GR, Selak L, Salo S. Reinforcement of surgical adhesive strips. J Dermatol Surg Oncol. 1986;12: 904-6.
- Moy RL, Quan MB. An evaluation of wound closure tapes. J Dermatol Surg Oncol. 1990;16:721-3.
- Lesesne CB. The postoperative use of wound adhesives. J Dermatol Surg Oncol. 1992;18:990.
- Katz KH, Desciak EB, Maloney ME. The optimal application of surgical adhesive tape strips. Dermatol Surg. 1999;25:686-8.
- Yavuzer R, Kelly C, Durrani N, Mittal V, Jackson IT, Remine S. Reinforcement of subcuticular continuous suture closure with surgical adhesive strips and gum mastic: is there any additional strength provided? Am J Surg. 2005;189:315-8.
- Patel N, Smith CE, Pinchak AC, Hancock DE. The influence of tape type and of skin preparation on the force required to dislodge angiocatheters. Can J Anaesth. 1994;41:738-41.
- James WD, White SW, Yanklowitz B. Allergic contact dermatitis to compound tincture of benzoin. J Am Acad Derm. 1984;11:847-50.
- Klein TG, Woehlck HJ, Pagel PS. Severe allergic contact dermatitis resulting from occupational exposure to tincture of benzoin aerosol spray in an anesthesiologist. J Anesth. 2009;23:292-4.
- Ryder M, Duley C. Evaluation of compatibility of a gum mastic liquid adhesive and liquid adhesive remover with an alcoholic chlorhexidine gluconate skin preparation. J Infusion Nursing. 2017;40:245-52.
- Deneau J, Craig A. Nursing survey reveals novel strategy in assisting adherence to best practices of CVC dressing management. Presented at: Institute for Healthcare Improvement National Forum; December 8-11, 2013; Orlando, FL.
- Pullen D. Quality Improvement Initiative to Improve Dressing Adherence Reveals Improved Dressing Adherence Observations on a Before-After Analysis. Presented at: Association for Vascular Access Annual Scientific Meeting, September 7-10, 2014; Washington DC.
- Niehaus S, McCord J. Improving Adhesion of Internal Jugular Dressings in the Intensive Care Unit. Presented at: Association for Vascular Access Annual Scientific Meeting, September 16-19, 2016;Orlando, FL.
- Browne B, Moffo H. Quality Improvement Initiative Results in Fewer Dressing Disruptions and Improved Adherence to Best Practices. Presented at: Greater Cincinnati AACN Chapter, 28th Annual Trends in Critical Care Conference, April 8, 2016; Cincinnati, OH.
- Bortz A, Hardinger K, Peltzer J. Impact of implementing Mastisol in central line dressing changes on central line-associated blood stream infections in progressive care units: a quality improvement project. Presented at: Magnetizing KC Symposium, February 24, 2015.
- Aldi R, Galvin K, Weintraub S, et al. Quality improvement initiative results in the standardization of processes for central line-associated bloodstream infection prevention and increased adherence to best practices. Presented at: AACN Horizons Conference, October 8-9, 2018; Manchester, NH.
- Jameson L. From PRN to routine…a vascular access team’s journey to reducing PRN central venous catheter dressing changes by adding to the vascular access tool box. Presented at: Association for Vascular Access Annual Scientific Meeting, September 15-18, 2018; Columbus, OH.
- Squires EN, Bruggeman S. Use of gum mastic medical adhesive to maintain central venous access device dressing integrity. Presented at: Association for Vascular Access Scientific Meeting, October 4-7, 2019; Las Vegas, NV.
- Boudreaux A. Ventriculostomy Dressing Process Improvement. Presented at the National Teaching Institute & Critical Care Exposition, May, 2013; Boston, MA.
- DeVries, M; Sarbenoff, J; Scott, N; Wickert, M; Hayes, L. Improving Vascular Access Dressing Integrity in the Acute Care Setting, Journal of Wound, Ostomy and Continence Nursing: June 28, 2021 – Volume Publish Ahead of Print – Issue – doi: 10.1097/WON.0000000000000787
- Vowels A. Impact of Using Gum Mastic Liquid Adhesive on Integrity & Durability of Driveline Dressings to Reduce Risk of Infection and Improve Quality of Life. Poster presentation at 67th Annual Conference ASAIO. Chicago, IL: June 8-11, 2022.
- Gamble JJ, McKay WP, Peeling A, Durr C, Krysak T, Guo R, Lange T, Cowen J, Bajwa JS. A comparison of methods used to secure pediatric endotracheal tubes using a live human dermal model. Can J Anaesth. 2021;68:645-52.