Mastisol® Liquid Adhesive

Mastisol Product Family

What is Mastisol?

Mastisol is a liquid medical adhesive used to secure dressings, tapes, and certain medical devices over an extended period of time.

Use of Mastisol offers the following benefits:

  • Reduced likelihood of dressing displacement and device dislodgement⁴
  • Minimized risk of device-related infection by creating a lasting occlusive barrier.⁵
  • Improved nurse efficiency with reduced time associated with unplanned dressing changes.⁸
  • Versatility to improve the adhesive power of a variety of adhesive tapes, dressings and, devices.³
  • Compatible with chlorhexidine gluconate (CHG)⁷
  • Low risk of adverse reactions and latex-free⁴

Instructions for Use

Security comes in four easy steps:

Crack: Place an individual vial blister pack on a hard surface with the label facing down. Gently apply pressure to the vial through the blister pack to crush the inner ampule to release Mastisol.

Peel: Peel back the lid of the blister pack and remove the vial using aseptic technique.

Apply: Turn the vial upside-down to dispense Mastisol onto the skin in a half-inch wide line.
Apply Mastisol to the outside border of where the dressing will be placed, avoiding the area immediately surrounding the catheter insertion site.
Allow Mastisol to dry completely, for approximately 20–30 seconds.

Dress: Per facility protocol, apply the dressing to the skin, ensuring edges are in contact with Mastisol.

For best results, use Detachol Adhesive Remover for removal.

Download IFU Pamphlet

Product Resources

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    Improve Patient Outcomes

    Use of Mastisol reduces likelihood of dressing displacement and device dislodgement¹²³⁴ creating a lasting occlusive barrier that minimizes risk of infection.⁵⁶⁷ Mastisol is non-water soluble and secures even in moist or moisture-prone areas and is compatible with Chlorhexidine Gluconate⁷

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    Increase Quality

    Mastisol promotes compliance with CDC guidelines, reducing workflow disruption.¹²³⁴ It is clinically-proven to improve the adhesive power of a variety of different adhesive tapes/dressings.³

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    Reduce Cost

    Mastisol can reduce product waste due to fewer unscheduled dressing changes resulting in overall supply cost savings and recovered nursing time.

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    Operating Room

    Wound Closure Strip Securement, ET Tube Securement, Sterile Field Drapes

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    Intensive Care Units

    Vascular Access Device Dressing Securement, ET Tube & NG Tube Securement, Fecal Management Bag & Foley Anchor Securement

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    Vascular Access Device Dressing Securement, Wound Dressing Securement

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    Emergency Room

    Wound Closure Strip Securement, Wound Dressing Securement, Chest Tube Securement

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    Vascular Access Device Dressing Securement, Wound Dressing Securement, ET Tube & NG Tube Securement

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    Respiratory Therapy

    ET Tube & NG Tube Securement

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    Vascular Access Team

    Vascular Access Device Dressing Securement

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    Wound Ostomy

    Ostomy Appliance Securement, Wound Dressing Securement, NPWT Drape Securement

Download the latest data and product information surrounding Mastisol Liquid Adhesive.

Free On-Demand Webinars featuring some of the finest thought-leaders in healthcare specialties such as Infection Prevention, Vascular Access, Surgical Care and more.

Here you will find a collection of issues we think acute caregivers want and need to know about. We understand the challenges faced by hospitals in the US today, and we want to deliver practical information that can be applied to your daily practice.

Ordering Information

Product SKUs 0496-0523-48 0496-0523-15 0496-0523-16 0496-0523-06
Product 48 x 2/3 mL Vial, Box 15 mL, Bottle 15 mL, Spray Bottle 2 oz, Bottle
Packer Qty 1 12 12 12


From the Eloquest Healthcare Blog


[1]Deneau J, Craig A. Nursing Survey Reveals Novel Strategy in Assisting Adherence to Best Practices of CVC Dressing Management. Poster presented at: Institute for Healthcare Improvement National Forum, December 8-11, 2013.

[2]Pullen D. Quality Improvement Initiative to Improve Dressing Adherence Reveals Improved Dressing Adherence Observations on a Before- After Analysis. Poster presented at: AVA Annual Scientific Meeting, September 7-10, 2014.
[3]Patel N. The influence of tape type and of skin preparation on the force required to dislodge angiocatheters. Can J Anaesth. 1994;41:8:738-741

[4]Lesesne CB. The postoperative use of wound adhesives: gum mastic versus benzoin, USP.J Dermatol Surg Onc. 1992;18(11):990.

[5]Timsit J. et al. Dressing disruption is a major risk factor for catheter-related infections. Crit Care Med. 2012;40(6):1701-1714.

[6]Browne B, Moffo H. Quality improvement initiative results in fewer dressing disruptions and improved adherence to best practices. Presented at: Greater Cincinnati AACN Chapter, 28th Annual Trends in Critical Care Conference, April 8, 2016.

[7]Ryder M, Duley C. Evaluation of compatibility of a gum mastic liquid adhesive and liquid adhesive remover with an alcoholic chlorhexidine gluconate skin preparation. J Infus Nurs. 2016;40(4):245-252.

[8]Nelson Squires E, Bruggeman S. Use of gum mastic medical adhesive to maintain central venous access device dressing integrity. Presented at: Association for Vascular Access Annual Scientific Meeting, October 4-7, 2019.